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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-RCC1 antibody produced in mouse

Monoclonal Anti-RCC1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0001104M1
规格纯度
clone 2F1, purified immunoglobulin, buffered aqueous solution
价格
4888.5 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-RCC1 antibody produced in mouse
Anti-regulator of chromosome condensation 1
Anti-CHC1
Anti-RCC1I
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Regulator of chromosome condensation 1 (RCC1) is a nuclear guanine nucleotide exchange factor for the small GTPase Ran enzyme. The gene is located on human chromosome 1p35.3. It is a 45 kDa protein.

免疫原

RCC1 (AAH07300, 312 a.a. ~ 421 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS

生化/生理作用

Regulator of chromosome condensation 1 (RCC1) interacts with chromatin and contributes to the formation of RanGTP gradients, which is required for nucleo-cytoplasmic transport, mitotic spindle formation and nuclear envelope reassembly following mitosis. It is an important cell cycle regulator. The protein functions as a tumor suppressor in gastric carcinoma.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

基本信息

MDL编号 MFCD01634139
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 2F1, monoclonal
形式 buffered aqueous solution
species reactivity human
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG1κ
GenBank?accession no. BC007300
UniProt登记号 P18754
运输 dry ice
储存温度 ?20℃
Gene Information human ... RCC1(1104)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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