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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-HES1 antibody produced in mouse

Monoclonal Anti-HES1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0003280M1
规格纯度
clone 4D9, purified immunoglobulin, buffered aqueous solution
价格
4888.5 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-HES1 antibody produced in mouse
Anti-hairy and enhancer of split 1, (Drosophila)
Anti-HHL
Anti-HES1
Anti-FLJ20408
Anti-HRY
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. (provided by RefSeq)
Hairy and enhancer of split-1 (HES1) is a transcriptional repressor. It is a member of the basic helix-loop-helix family of transcription factors. This gene is mapped to human chromosome 3q29.

免疫原

HES1 (NP_005515, 36 a.a. ~ 142 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGH

应用

Monoclonal Anti-HES1 antibody has been used in western blotting.

生化/生理作用

Hairy and enhancer of split-1 (HES1) is required for regulating NPC (neural progenitor cells) fate and fetal brain development. This gene also helps to maintain the undifferentiated and proliferative status of NPCs. Absence of HES1 is linked with poor prognosis in colorectal adenocarcinoma.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD03096856
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 4D9, monoclonal
形式 buffered aqueous solution
species reactivity human
technique(s) indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2bκ
GenBank?accession no. NM_005524
UniProt登记号 Q14469
运输 dry ice
储存温度 ?20℃
Gene Information human ... HES1(3280)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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