半岛bd体育手机客户端 说明
生化/生理作用
NMDA 谷氨酸受体拮抗剂。
分析说明
Assay (alkalimetric, calculated on dried substance): 98.5 - 101.0 %
Identity (IR-spectrum): passes test
Identity (Chloride): passes test
Appearance: white to almost white crystalline powder or colorless crystals
Appearance of solution (25 g/l, water): clear and not more intense in color than reference solution BY?
Spec. rotation (α 20/D, 80?g/l, hydrochloric acid 250?g/l, calc. on dried substance): +5.5 to +7.0
Spec. rotation (α 25/D, 80?g/l, hydrochloric acid 6?mol/l, calc. on dried substance): +5.7 to +6.8
Sulfate (SO?): ≤ 300 ppm
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 20 ppm
Related Compounds, total (TLC): ≤ 0.5 %
Ninhydrin-positive substances (LC)(impurity A (570 nm)): ≤ 0.5 %
Ninhydrin-positive substances (LC)(any ninhydrin-positive impurity): ≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm)): ≤ 0.02 %
Ninhydrin-positive substances (LC)(total impurities): ≤ 1.0 %
Residual solvents (ICH Q3C): excluded by manufacturing proces
Sulfated ash (600?°C): ≤ 0.1 %
Loss on drying (Vacuum Bacterial endotoxins: ≤ 6.0 I.U./g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph.?Eur., USP.
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 线性分子式 | HSCH2CH(NH2)COOH · HCl · H2O |
| 分子量 | 175.63 |
| Beilstein | 5158059 |
| MDL编号 | MFCD00065606 |
| EC索引号 | 200-157-7 |
半岛bd体育手机客户端 性质
| 质量水平 | 500 |
| agency | JP Ph. Eur. USP |
| 蒸汽压 | <0.1 hPa ( 20 ℃) |
| 半岛bd体育手机客户端 线 | EMPROVE?EXPERT |
| 测定 | 98.5-101.0% dry basis (alkalimetric) |
| 形式 | crystalline powder |
| pH值(酸碱度) | 0.8-1.2 (20 ℃, 100 g/L in H2O) |
| mp | 168-170 ℃ |
| 溶解性 | 650 g/L |
| 密度 | 1.54 g/cm3 |
| 堆积密度 | 780 kg/m3 |
| 痕量阴离子 | sulfate (SO42-): ≤300 ppm |
| 痕量阳离子 | Fe: ≤20 ppm heavy metals (as Pb): ≤10 ppm |
| 储存温度 | 2-30℃ |
| SMILES string | O.Cl.N[C@@H](CS)C(O)=O |
| InChI | 1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1 |
| InChI key | QIJRTFXNRTXDIP-JIZZDEOASA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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