浜у搧璇存槑
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PAX-5 encodes for B-cell-specific activator protein (BSAP), a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5. PAX-5 is not detected in multiple myeloma and solitary plasmacytoma, making it useful for such differentiation. Diffuse large B-cell lymphomas do express PAX-5, save for those with terminal B-cell differentiation. T-cell neoplasms do not stain with anti-PAX-5. There is a strong association with CD20 expression.
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 IVD |
 IVD |
 IVD |
 RUO |
鑱旂郴
PAX-5 Positive Control Slides, Product No. 312S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
澶栧舰
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
鍏朵粬璇存槑
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
娉曞緥淇℃伅
Cell Marque is a trademark of sigma-aldrich Co. LLC
鍩烘湰淇℃伅
| NACRES | NA.41 |
浜у搧鎬ц川
| 璐ㄩ噺姘村钩 | 500 100 |
| 鐢熺墿鏉ユ簮 | mouse |
| 鍋惰仈鐗?/td> | unconjugated |
| 鎶椾綋褰㈠紡 | culture supernatant |
| antibody product type | primary antibodies |
| 鍏嬮殕 | 24, monoclonal |
| 鎻忚堪 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 褰㈠紡 | buffered aqueous solution |
| species reactivity | human |
| 鍖呰 | bottle of 1.0 mL predilute (312M-17) bottle of 7.0 mL predilute (312M-18) |
| manufacturer/tradename | Cell Marque? |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| 鍚屼綅绱?浜氬瀷 | IgG1 |
| 鎺у埗 | tonsil |
| 杩愯緭 | wet ice |
| 鍌ㄥ瓨娓╁害 | 2-8鈩傸/td> |
| 鍙鍖朁/td> | nuclear |
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