Cytokeratin 5 &6 (D5 &16B4) Mouse Monoclonal Antibody

半岛bd体育手机客户端 说明

一般描述

Anti-CK 5 & 6 positivity is seen in 65% to 100% of epithelioid mesotheliomas, in 0% to 19% of lung adenocarcinomas, and in 22% to 80% of serous carcinoma of the ovary and peritoneum. Keratin 5 & 6 expression in lung adenocarcinoma is not common, and when it occurs, the reaction is usually confined to small focal areas or scattered cells. The most probable cause of this finding is the presence of squamous differentiation of lung adenocarcinoma. Anti-CK 5 & 6 positivity has been useful in recognizing squamous cell carcinoma of the skin. Less than 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5 & 6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy. Anti-CK 5 & 6 is a useful marker to distinguish lung squamous cell carcinoma from lung adenocarcinoma and large cell carcinoma within a panel including antibodies against TTF-1, Napsin A, p63, SOX-2, desmocollin3, and desmoglein3.

质量

IVD

IVD

IVD

RUO

联系

Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	500 100
生物来源	mouse
偶联物	unconjugated
抗体形式	diluted ascites fluid
antibody product type	primary antibodies
克隆	D5 & 16B4, monoclonal
描述	For In Vitro Diagnostic Use in Select Regions (See Chart)
形式	buffered aqueous solution
species reactivity	human
包装	vial of 0.1 mL concentrate (356M-14) vial of 0.5 mL concentrate (356M-15) bottle of 1.0 mL predilute (356M-17) vial of 1.0 mL concentrate (356M-16) bottle of 7.0 mL predilute (356M-18)
manufacturer/tradename	Cell Marque?
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
同位素/亚型	IgG1
控制	mesothelioma
运输	wet ice
储存温度	2-8℃
可视化	cytoplasmic