浜у搧璇存槑
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This antibody reacts with a 53 kDa protein which forms a part of the family of tetraspan moieties. The antigen was originally designated as a lysosomal membrane protein characterized as an activation dependent platelet surface antigen. In fact the CD63 antigen has a diverse distribution on the surface and in the cytoplasm of many cell types including lymphoid, myeloid, endothelial cells and melanoma. It has been quite useful in identifying malignant melanoma. Mete et al. found it useful in differentiating renal oncocytomas (RO) from eosinophilic renal cell carcinomas (eRCC). In his series of 35 ROs, 94% demonstrated apical and/or polar CD63 positivity. Of his 77 eRCCs, 96% showed diffuse cytoplasmic staining.
璐ㄩ噺
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鑱旂郴
CD63 Positive Control Slides, Product No. 263S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
澶栧舰
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
鍒跺璇存槑
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鍏朵粬璇存槑
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
娉曞緥淇℃伅
Cell Marque is a trademark of sigma-aldrich Co. LLC
鍩烘湰淇℃伅
NACRES | NA.41 |
浜у搧鎬ц川
璐ㄩ噺姘村钩 | 500 100 |
鐢熺墿鏉ユ簮 | mouse |
鍋惰仈鐗?/td> | unconjugated |
鎶椾綋褰㈠紡 | diluted ascites fluid |
antibody product type | primary antibodies |
鍏嬮殕 | NKI/C3, monoclonal |
鎻忚堪 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
褰㈠紡 | buffered aqueous solution |
species reactivity | human |
鍖呰 | vial of 0.1 mL concentrate (263M-14) vial of 0.5 mL concentrate (263M-15) bottle of 1.0 mL predilute (263M-17) vial of 1.0 mL concentrate (263M-16) bottle of 7.0 mL predilute (263M-18) |
manufacturer/tradename | Cell Marque? |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
鍚屼綅绱?浜氬瀷 | IgG1κ |
鎺у埗 | melanoma |
杩愯緭 | wet ice |
鍌ㄥ瓨娓╁害 | 2-8鈩傸/td> |
鍙鍖朁/td> | cytoplasmic, membranous |