TSH (EP254) Rabbit Monoclonal Primary Antibody

浜у搧璇存槑

涓€鑸弿杩?/p>

Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit, which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones: Follicle stimulating hormone and luteinizing hormone and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors and the differential identification of primary and metastatic tumors in the pituitary gland.^1-5

璐ㄩ噺

IVD

RUO

鑱旂郴

TSH Positive Control Slides, Product No. 211S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

澶栧舰

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

鍒跺璇存槑

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

鍏朵粬璇存槑

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

娉曞緥淇℃伅

Cell Marque is a trademark of sigma-aldrich Co. LLC

鍩烘湰淇℃伅

NACRES

NA.41

浜у搧鎬ц川

鐢熺墿鏉ユ簮	rabbit
璐ㄩ噺姘村钩	500 100
鍋惰仈鐗?/td>	unconjugated
鎶椾綋褰㈠紡	culture supernatant
antibody product type	primary antibodies
鍏嬮殕	EP254, monoclonal
鎻忚堪	(For In Vitro Diagnostic Use in Select Regions (See Chart))
褰㈠紡	buffered aqueous solution
species reactivity	human
鍖呰	bottle of 1.0 mL predilute (211R-17) bottle of 7.0 mL predilute (211R-18) vial of 0.1 mL concentrate (211R-14) vial of 0.5 mL concentrate (211R-15) vial of 1.0 mL concentrate (211R-16)
manufacturer/tradename	Cell Marque^?
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
鍚屼綅绱?浜氬瀷	IgG
杩愯緭	wet ice
鍌ㄥ瓨娓╁害	2-8鈩傸/td>