Thrombomodulin (1009) Mouse Monoclonal Antibody

半岛bd体育手机客户端 说明

一般描述

Thrombomodulin is a transmembrane glycoprotein composed of 575 amino acids (molecular weight 75 kD with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytiotrophoblasts of human placenta also express thrombomodulin. Several immunohistochemical endothelial markers are currently available and anti-thrombomodulin serves as another such marker, staining blood and lymphatic channels consistently. Anti-thrombomodulin has demonstrated positivity in 100% of benign vascular tumors (pyogenic granuloma and hemangioma) and 94% of malignant vascular tumors (Kaposi′s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. There has also been recent interest in the use of anti-thrombomodulin as an immunohiostochemical marker for mesothelial cells and malignant mesotheliomas. Anti-thrombomodulin is immunoexpressed in a variety of other tumors including squamous cell carcinomas of the lung, synovial sarcoma, transitional cell carcinoma, renal cell carcinomas and thymomas.

质量

IVD

IVD

IVD

RUO

联系

Thrombomodulin Positive Control Slides, Product No. 339S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	500 100
生物来源	mouse
偶联物	unconjugated
抗体形式	culture supernatant
antibody product type	primary antibodies
克隆	1009, monoclonal
描述	For In Vitro Diagnostic Use in Select Regions (See Chart)
形式	buffered aqueous solution
species reactivity	human
包装	vial of 0.1 mL concentrate (339M-14) vial of 0.5 mL concentrate (339M-15) bottle of 1.0 mL predilute (339M-17) vial of 1.0 mL concentrate (339M-16) bottle of 7.0 mL predilute (339M-18)
manufacturer/tradename	Cell Marque?
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型	IgG1κ
控制	bladder, mesothelioma
运输	wet ice
储存温度	2-8℃
可视化	membranous