SDHB (EP288) Rabbit Monoclonal Primary Antibody

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Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.

璐ㄩ噺

IVD

RUO

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Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

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璐ㄩ噺姘村钩	500 100
鐢熺墿鏉ユ簮	rabbit
鍋惰仈鐗?/td>	unconjugated
鎶椾綋褰㈠紡	culture supernatant
antibody product type	primary antibodies
鍏嬮殕	EP288, monoclonal
鎻忚堪	For In Vitro Diagnostic Use in Select Regions
褰㈠紡	buffered aqueous solution
species reactivity	human
鍖呰	vial of 0.1 mL concentrate (466R-14) vial of 0.1 mL concentrate Research Use Only (466R-14-RUO) vial of 0.5 mL concentrate (466R-15) vial of 1.0 mL concentrate (466R-16) vial of 1.0 mL concentrate Research Use Only (466R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO) vial of 1.0 mL pre-dilute ready-to-use (466R-17) vial of 7.0 mL pre-dilute ready-to-use (466R-18) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO)
manufacturer/tradename	Cell Marque^?
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
鍚屼綅绱?浜氬瀷	IgG
鎺у埗	GIST
杩愯緭	wet ice
鍌ㄥ瓨娓╁害	2-8鈩傸/td>
鍙鍖朁/td>	cytoplasmic