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SALL4 (6E3) Mouse Monoclonal Antibody

鍝佺墝
Sigma-Aldrich
璐у彿
385M-1
鍖呰鍨嬪彿
瑙勬牸绾害
鍙傝€冧环鏍稽/div>
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淇冮攢
鏈嶅姟
  • 鈭欬/span>鍘熷巶淇濊瘉
  • 鈭欬/span>鍖呴偖
  • 鈭欬/span>澧炲€肩◣绁?/li>
鏁伴噺
- +
浜у搧鍚嶇О锛欬/div>
SALL4 (6E3) Mouse Monoclonal Antibody
浜у搧浠嬬粛锛欬/div>

浜у搧璇存槑

涓€鑸弿杩?/p>

SALL4 is a zinc finger transcription factor. Anti-SALL4 demonstrates 100% sensitivity and stains more than 90% tumor cells in all intratubular germ cell neoplasia, seminomas/dysgerminomas, embryonal carcinomas, and yolk sac tumor (YST) (both pediatric and postpubertal). Anti-SALL4 also stains most cases of teratoma and the mononucleated trophoblastic cells in choriocarcinomas. In contrast, non-germ cell tumors show no anti-SALL4 staining. Most non-testicular tumors from various organs and sites are negative for anti-SALL4, though an occasional carcinoma or sarcoma may show weak anti-SALL4 staining in less than 25% of tumor cells. In normal testicular tissue, positive, weak anti-SALL4 staining is observed in spermatogonia. In addition, a few (<5%) primary spermatocytes showed dot-like weak anti-SALL4 staining. Secondary spermatocytes, spermatids, spermatozoa, and Sertoli cells are negative for anti-SALL4. Leydig cells, rete testis, epididymis, spermatic cord fibroblasts, blood vessels, and hematopoietic cells are negative for anti-SALL4.

璐ㄩ噺


IVD

IVD

IVD

RUO

鑱旂郴

SALL4 Positive Control Slides, Product No. 385S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

澶栧舰

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

鍒跺璇存槑

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鍏朵粬璇存槑

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

娉曞緥淇℃伅

Cell Marque is a trademark of sigma-aldrich Co. LLC

鍩烘湰淇℃伅

NACRES NA.41

浜у搧鎬ц川

璐ㄩ噺姘村钩 500
100
鐢熺墿鏉ユ簮 mouse
鍋惰仈鐗?/td> unconjugated
鎶椾綋褰㈠紡 culture supernatant
antibody product type primary antibodies
鍏嬮殕 6E3, monoclonal
鎻忚堪 For In Vitro Diagnostic Use in Select Regions (See Chart)
褰㈠紡 buffered aqueous solution
species reactivity human
鍖呰 vial of 0.1 mL concentrate (385M-14)
vial of 0.5 mL concentrate (385M-15)
bottle of 1.0 mL predilute (385M-17)
vial of 1.0 mL concentrate (385M-16)
bottle of 7.0 mL predilute (385M-18)
manufacturer/tradename Cell Marque?
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
鍚屼綅绱?浜氬瀷 IgG1
鎺у埗 dysgerminoma, seminoma
杩愯緭 wet ice
鍌ㄥ瓨娓╁害 2-8鈩傸/td>
鍙鍖朁/td> nuclear

Sigma-Aldrich

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