浜у搧璇存槑
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SALL4 is a zinc finger transcription factor. Anti-SALL4 demonstrates 100% sensitivity and stains more than 90% tumor cells in all intratubular germ cell neoplasia, seminomas/dysgerminomas, embryonal carcinomas, and yolk sac tumor (YST) (both pediatric and postpubertal). Anti-SALL4 also stains most cases of teratoma and the mononucleated trophoblastic cells in choriocarcinomas. In contrast, non-germ cell tumors show no anti-SALL4 staining. Most non-testicular tumors from various organs and sites are negative for anti-SALL4, though an occasional carcinoma or sarcoma may show weak anti-SALL4 staining in less than 25% of tumor cells. In normal testicular tissue, positive, weak anti-SALL4 staining is observed in spermatogonia. In addition, a few (<5%) primary spermatocytes showed dot-like weak anti-SALL4 staining. Secondary spermatocytes, spermatids, spermatozoa, and Sertoli cells are negative for anti-SALL4. Leydig cells, rete testis, epididymis, spermatic cord fibroblasts, blood vessels, and hematopoietic cells are negative for anti-SALL4.
璐ㄩ噺
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鑱旂郴
SALL4 Positive Control Slides, Product No. 385S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
澶栧舰
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
鍒跺璇存槑
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鍏朵粬璇存槑
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
娉曞緥淇℃伅
Cell Marque is a trademark of sigma-aldrich Co. LLC
鍩烘湰淇℃伅
NACRES | NA.41 |
浜у搧鎬ц川
璐ㄩ噺姘村钩 | 500 100 |
鐢熺墿鏉ユ簮 | mouse |
鍋惰仈鐗?/td> | unconjugated |
鎶椾綋褰㈠紡 | culture supernatant |
antibody product type | primary antibodies |
鍏嬮殕 | 6E3, monoclonal |
鎻忚堪 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
褰㈠紡 | buffered aqueous solution |
species reactivity | human |
鍖呰 | vial of 0.1 mL concentrate (385M-14) vial of 0.5 mL concentrate (385M-15) bottle of 1.0 mL predilute (385M-17) vial of 1.0 mL concentrate (385M-16) bottle of 7.0 mL predilute (385M-18) |
manufacturer/tradename | Cell Marque? |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
鍚屼綅绱?浜氬瀷 | IgG1 |
鎺у埗 | dysgerminoma, seminoma |
杩愯緭 | wet ice |
鍌ㄥ瓨娓╁害 | 2-8鈩傸/td> |
鍙鍖朁/td> | nuclear |