浜у搧璇存槑
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Paired-like homeobox 2B (PHOX2B) is a transcription factor located on chromosome 4p13 which is crucial to the formation of autonomic ganglia in the autonomic nervous system (ANS). PHOX2B gene is strictly expressed in neural crest derivatives committed to the noradrenergic phenotype. The PHOX2B gene encodes a paired-like homeo-domain transcription factor with an extra-axial expression pattern restricted to the ANS. Neuroblasts of peripheral neuroblastic tumors are derived from the sympathoadrenal lineage, a division of the ANS. PHOX2B has been observed in peripheral neuroblastic tumors, neuroblastomas, paragangliomas, ganglioneuroblastomas, ganglioneuromas and pheochromocytomas. PHOX2B has been reported to be negative in other small round blue cell tumors.
璐ㄩ噺
 IVD |
 IVD |
 IVD |
 RUO |
鑱旂郴
PHOX2B Positive Control Slides, Product No. 422S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
澶栧舰
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
鍒跺璇存槑
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鍏朵粬璇存槑
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
娉曞緥淇℃伅
Cell Marque is a trademark of sigma-aldrich Co. LLC
浜у搧鎬ц川
| 璐ㄩ噺姘村钩 | 500 100 |
| 鐢熺墿鏉ユ簮 | rabbit |
| 鍋惰仈鐗?/td> | unconjugated |
| 鎶椾綋褰㈠紡 | culture supernatant |
| antibody product type | primary antibodies |
| 鍏嬮殕 | EP312, monoclonal |
| 鎻忚堪 | For In Vitro Diagnostic Use in Select Regions |
| 褰㈠紡 | buffered aqueous solution |
| species reactivity | human |
| 鍖呰 | vial of 0.1 mL concentrate (422R-14) vial of 0.1 mL concentrate Research Use Only (422R-14-RUO) vial of 0.5 mL concentrate (422R-15) vial of 1.0 mL concentrate (422R-16) vial of 1.0 mL concentrate Research Use Only (422R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (422R-17-RUO) vial of 1.0 mL pre-dilute ready-to-use (422R-17) vial of 7.0 mL pre-dilute ready-to-use (422R-18) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (422R-18-RUO) |
| manufacturer/tradename | Cell Marque? |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated) |
| 鍚屼綅绱?浜氬瀷 | IgG |
| 鎺у埗 | neuroblastoma |
| 杩愯緭 | wet ice |
| 鍌ㄥ瓨娓╁害 | 2-8鈩傸/td> |
| 鍙鍖朁/td> | nuclear |
瀹夊叏淇℃伅
| 鍌ㄥ瓨鍒嗙被浠ｇ爜 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闂偣(F) | Not applicable |
| 闂偣(C) | Not applicable |
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