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位置: 首页> 品牌> Sigma-Aldrich> IMP3 (EP286) Rabbit Monoclonal Primary Antibody

IMP3 (EP286) Rabbit Monoclonal Primary Antibody

品牌
Sigma-Aldrich
货号
433R-1
包装型号
规格纯度
价格
2047.96 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
IMP3 (EP286) Rabbit Monoclonal Primary Antibody
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Insulin-like growth factor II mRNA binding protein 3 (IMP3) is an oncofetal RNA-binding protein that regulates targets such as insulin-like growth factor-2 and beta-actin. IMP3 expression is at its highest during embryogenesis and silenced in normal human tissues (fibroblasts, lymphocytes, and testes are exceptions).1IMP3 plays a major role in early embryogenesis involving the development of the intestine, thymus, pancreas, and kidneys.2IMP3 mRNA transcript and protein have been demonstrated in high levels in pancreatic cancer tissues but not in benign lesions of the pancreas, chronic pancreatitis, or normal pancreatic tissues.1In a study of IMP3 being used to distinguish between pancreatic ductal adenocarcinoma from chronic sclerosing pancreatitis, IMP3 was found to have high sensitivity and specificity for pancreatic ductal adenocarcinoma and detected pancreatic ductal adenocarcinoma metastases.2IMP3 expression has also been found in a variety of other human cancers including renal cell carcinoma, adenocarcinoma of the uterine cervix, endometrial carcinoma, adenocarcinoma of the esophagus, malignant melanoma, Merkel cell carcinoma, urothelial carcinoma, neuroendocrine carcinoma of the lung, adenocarcinoma of the pancreas, and triple negative breast cancer.1,2

质量


IVD

IVD

IVD

RUO

联系

IMP3 Positive Control Slides, Product No. 433S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 500
100
偶联物 unconjugated
抗体形式 culture supernatant
antibody product type primary antibodies
克隆 EP286, monoclonal
描述 (For In Vitro Diagnostic Use in Select Regions (See Chart))
形式 buffered aqueous solution
species reactivity human
包装 vial of 0.1 mL concentrate (433R-14)
vial of 0.5 mL concentrate (433R-15)
bottle of 1.0 mL predilute (433R-17)
vial of 1.0 mL concentrate (433R-16)
bottle of 7.0 mL predilute (433R-18)
manufacturer/tradename Cell Marque?
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型 IgG
控制 pancreatic ductal adenocarcinoma, placenta
运输 wet ice
储存温度 2-8℃
可视化 cytoplasmic, membranous

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