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The monoclonal antibody against IgD reacts with immunoglobin D delta chains. In tonsil and lymph node, immunohistochemical staining for IgD immunoglobulin heavy chain is usually used to highlight the tonsil and nodal architecture since the IgD antibody stains mantle zone cells in secondary follicles and mantle cells in primary follicles.1It has been reported that IgD can be detected in the surface/cytoplasm of neoplastic cells of common small B lymphoid cell lymphomas, such as small lymphocytic lymphoma, mantle cell lymphoma, marginal zone lymphoma (especially splenic marginal zone lymphoma), and follicular lymphoma.1-2IgD expression in L & P cells of nodular lymphocyte predominant Hodkin lymphoma has been seen in subsets of cases (27% to 71.4%).1-3The IgD positive L & P cells are usually located in the extrafollicular area with a relatively T-cell-rich background1,3IgD expression is rarely seen in T-cell rich B-cell lymphoma. Studies have demonstrated that Reed-Sternberg cells of classic Hodgkin lymphoma were negative for IgD1,3IgD multiple myeloma is a rare bone marrow plasma cell dyscrasia and can be identified by the IgD antibody, especially when a dry tap is encountered.4
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 IVD |
 IVD |
 IVD |
 RUO |
鑱旂郴
IgD Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
澶栧舰
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
鍒跺璇存槑
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For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
娉曞緥淇℃伅
Cell Marque is a trademark of sigma-aldrich Co. LLC
鍩烘湰淇℃伅
| NACRES | NA.41 |
浜у搧鎬ц川
| 鐢熺墿鏉ユ簮 | rabbit |
| 璐ㄩ噺姘村钩 | 500 100 |
| 鍋惰仈鐗?/td> | unconjugated |
| 鎶椾綋褰㈠紡 | culture supernatant |
| antibody product type | primary antibodies |
| 鍏嬮殕 | EP173, monoclonal |
| 鎻忚堪 | (For In Vitro Diagnostic Use in Select Regions (See Chart)) |
| 褰㈠紡 | buffered aqueous solution |
| species reactivity | human |
| 鍖呰 | bottle of 1.0 mL predilute (268R-17) bottle of 7.0 mL predilute (268R-18) vial of 0.1 mL concentrate (268R-14) vial of 0.5 mL concentrate (268R-15) vial of 1.0 mL concentrate (268R-16) |
| manufacturer/tradename | Cell Marque? |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| 鍚屼綅绱?浜氬瀷 | IgG |
| 杩愯緭 | wet ice |
| 鍌ㄥ瓨娓╁害 | 2-8鈩傸/td> |
瀹夊叏淇℃伅
| 鍌ㄥ瓨鍒嗙被浠ｇ爜 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闂偣(F) | Not applicable |
| 闂偣(C) | Not applicable |
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