浜у搧璇存槑
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Glycophorins A (GPA) and B (GPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and SU blood groups. Glycophorins span the membrane and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin-like surface and it has been suggested this provides a barrier to cell fusion thus minimizing aggregation between red blood cells in the circulation. Anti-glycophorin A has been used to characterize erythroid cell development and in the diagnosis of erythroid leukemias.
璐ㄩ噺
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鑱旂郴
Glycophorin A Positive Control Slides, Product No. 260S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
澶栧舰
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
鍒跺璇存槑
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鍏朵粬璇存槑
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
娉曞緥淇℃伅
Cell Marque is a trademark of sigma-aldrich Co. LLC
鍩烘湰淇℃伅
NACRES | NA.41 |
浜у搧鎬ц川
璐ㄩ噺姘村钩 | 500 100 |
鐢熺墿鏉ユ簮 | mouse |
鍋惰仈鐗?/td> | unconjugated |
鎶椾綋褰㈠紡 | culture supernatant |
antibody product type | primary antibodies |
鍏嬮殕 | GA-R2, monoclonal |
鎻忚堪 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
褰㈠紡 | buffered aqueous solution |
species reactivity | human |
鍖呰 | vial of 0.1 mL concentrate (260M-14) vial of 0.5 mL concentrate (260M-15) bottle of 1.0 mL predilute (260M-17) vial of 1.0 mL concentrate (260M-16) bottle of 7.0 mL predilute (260M-18) |
manufacturer/tradename | Cell Marque? |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
鍚屼綅绱?浜氬瀷 | IgG2bκ |
鎺у埗 | bone marrow |
杩愯緭 | wet ice |
鍌ㄥ瓨娓╁害 | 2-8鈩傸/td> |
鍙鍖朁/td> | membranous |