纯度规格:A cell-permeable compound that prevents the transfer of SUMO from the E2 thioester to the substrate without affecting SUMO-activating enzyme E1 (SAE-1/2) or E2 Ubc9-SUMO thioester formation.
纯度规格:A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC
50= 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.
纯度规格:An anti-bacterial compound that targets NAD(P)H-dependent enoyl acyl carrier protein reductase (ENR) resulting in the inhibition of bacterial fatty acid synthase.
纯度规格:Acid Ceramidase Inhibitor, BOC, CAS 1644158-57-5, is a cell-permeable, potent inhibitor of acid ceramidase (IC
50= 79 nM against HEK293 lysosomal lysate AC activity).
纯度规格:A cell-permeable compound that directly and reversibly interacts with miRNA binding domain of Argonaute-2 (K
d= 126 μM) and inhibits binding of miR-20a, miR-26a, miR-107, miR-223 &let-7a to Ago2.
纯度规格:Enhances BMP-2 associated signaling by inhibiting Smurf1-mediated Smad1/5 ubiquitination and thereby prolonging the half-life of Smad1 and 5. in 48 h).