纯度规格：InSolution
TMY-27632, Sterile-Filtered, Cell Culture-Tested, CAS 146986-50-7, is a 10 mM sterile-filtered solution of Y-27632 in H
2O. Acts as an inhibitor of Rho kinases (Ki = 140 nM for p160ROCK).
纯度规格：A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (~ 5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.
纯度规格：A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC
50= 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).
纯度规格：A cell-permeable, direct, non-covalent inhibitor of Keap1-Nrf2 protein-protein interaction (Kd = 1 μM) that causes the dissociation of Nrf2 from keap1 in the cytosol.
纯度规格：A cell-permeable compound that prevents various bacterial toxins from exerting their cytotoxic activity by blocking endosomal trafficking/maturation into acidified late endosomes.
纯度规格：A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC
50= 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).
纯度规格：A cell-permeable neomycin derived artificial nucleobase conjugate. Inhibits the production of oncogenic miRNAs 372 (IC
50= 2.4 μM) by binding to pre-miRNAs and interrupts processing by Dicer.
纯度规格：A cell-permeable inhibitor of nonsense-mediated mRNA decay (NMD) that enhances the stability of premature termination codon mutated p53 mRNA in N417 and HDQP-1 cells.
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