纯度规格:mTOR Activator, MHY1485, CAS Number: 326914-06-1, is a cell-permeable activator of mTOR that inhibits autophagy by suppressing the fusion between autophagosomes and lysosomes.
纯度规格:NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7 nM).
纯度规格:A cell permeable dual activator of protein kinase R (PKR) and protein kinase R like kinase (PERK). Induces the phosphorylation of IκBα and thereby activates NF-κB pathway.
纯度规格:RIP1 Inhibitor II, 7-Cl-O-Nec-1, CAS 852391-15-2, is a cell-permeable, highly selective RIP1 inhibitor. Blocks RIP1-dependent necroptosis (EC50 = 206 nM in Jurkat cells).
纯度规格:UCOE (Ubiquitous Chromatin Opening Elements) technology is a breakthrough solution for sustained recombinant protein production and cell line development in mammalian protein expression systems.
纯度规格:A cell permeable, highly potent, and very selective inhibitor of breast tumor kinase (Brk; IC
50= 3.15 nM). Displays anti-proliferative activity against multiple breast cancer cell lines.
纯度规格:A cell-permeable inhibitor repressor element-1 silencing transcription factor (REST). Targets REST degradation, but not its expression or binding to repressor element binding sequence.