纯度规格:JAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC
50= 15 nM), JAK2 (IC
50= 1 nM), JAK3 (K
i= 5 nM) and Tyk2 (IC
5
纯度规格:An immunosuppressive agent that inhibits
de novopurine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP.