蛋白质/抗原/多肽 >> 重组蛋白
重组粘附分子IgG样结构域蛋白3
半岛bd体育手机客户端 介绍
基因名:
Amigo3 半岛bd体育手机客户端 别名: Amigo3; adhesion molecule with Ig like domain 3; adhesion molecule with Ig like domain 3; amphoterin-induced protein 3; AMIGO-3; alivin-3; amphoterin induced gene and ORF 3; transmembrane protein AMIGO3; 粘附分子IgG样结构域蛋白3; 背景信息:
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction.
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