蛋白质/抗原/多肽 >> 重组蛋白
重组Schlafen家族14蛋白
半岛bd体育手机客户端 介绍
基因名:
Slfn14 半岛bd体育手机客户端 别名: Gm20; Slfn14-ps; Slfn14; schlafen 14; schlafen 14; protein SLFN14; Schlafen family member 14, CAST_EiJ strain specific; Schlafen family member 14, WSB_EiJ strain specific; schlafen family member 14, pseudogene; Schlafen家族14; 背景信息:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
标签:His-tag |
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