蛋白质/抗原/多肽 >> 重组蛋白
重组9号染色体开放阅读框117蛋白
半岛bd体育手机客户端 介绍
基因名:
Cfap157 半岛bd体育手机客户端 别名: 1700019L03Rik; Cfap157; cilia and flagella associated protein 157; cilia and flagella associated protein 157; cilia- and flagella-associated protein 157; 9号染色体开放阅读框117; 背景信息:
C9orf117 is a 520 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding C9orf117 maps to human chromosome 9q34.11. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
标签:His-tag |
相关半岛bd体育手机客户端
|