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蛋白质/抗原/多肽 >> 重组蛋白
重组谷氨酸受体δ2/GluR-δ2蛋白
重组谷氨酸受体δ2/GluR-δ2蛋白图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Recombinant Grid2ip
Recombinant glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1 protein
半岛bd体育手机客户端 介绍
基因名:

Grid2ip


半岛bd体育手机客户端 别名:

Grid2ip; glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1; glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1; delphilin; GluR-delta2 philic-protein; L-delphilin; glutamate receptor, ionotropic, delta 2-interacting protein 1; 谷氨酸受体δ2/GluR-δ2;


背景信息:
Grid2ip is a postsynaptic scaffolding protein that contains one formin homology 2 (FH2) domain and two PDZ (postsynaptic density-95/discs-large/ZO-1) domains. Expressed in Purkinje cells of the cerebellum and localizing specifically to parallel fiber synapses, Grid2ip interacts with the C-terminus of GluR-Delta 2 and, via this interaction, links GluR-Delta 2 with various signaling molecules and the Actin cytoskeleton. GluR-Delta 2 is a glutamate receptor with an important role in motor learning, cerebellar wiring and synaptic plasticity. Due to alternative splicing events, three Grid2ip isoforms exist, namely L-delphilin, S-delphilin (or delphilin-Alpha) and delphilin-Beta. Each isoform exhibits individual expression patterns and protein interactions. Isoform 2, delphilin-Alpha, is palmytoylated, a modification that is essential for the enhanced expression of GluR-Delta 2 on the cell surface. This modification of delphilin-Alpha also mediates the accumulation of delphilin-Alpha in dendritic spines.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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