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蛋白质/抗原/多肽 >> 重组蛋白
重组含亮氨酸神经胶质瘤失活蛋白4
重组含亮氨酸神经胶质瘤失活蛋白4图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant LGI4
Recombinant leucine rich repeat LGI family member 4 protein
半岛bd体育手机客户端 介绍
基因名:

LGI4


半岛bd体育手机客户端 别名:

AMC1; AMCNMY; LGIL3; LGI4; leucine rich repeat LGI family member 4; leucine rich repeat LGI family member 4; leucine-rich repeat LGI family member 4; LGI1-like protein 3; leucine-rich glioma-inactivated gene 4; leucine-rich glioma-inactivated protein 4; 含亮氨酸神经胶质瘤失活蛋白4;


背景信息:
LGI4, also known as leucine-rich glioma-inactivated protein 4, is a 537 amino acid secreted glycosylated protein that is widely expressed, with highest levels found within the nervous system. Interestingly, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation. LGI4 shares significant homology with its other family members, LGI1, LGI2 and LGI3. Significantly, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, given the sequence similarity of LGI4, it is likely that it also may be implicated in the pathology of seizures. LGI4 is localized subcellularly to the Golgi, ER and vesicles. There are two isoforms of LGI4 that are produced as a result of alternative splicing events.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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