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蛋白质/抗原/多肽 >> 重组蛋白
重组E3连接酶抑制素受体2蛋白
重组E3连接酶抑制素受体2蛋白图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Recombinant HECTD2
Recombinant HECT domain E3 ubiquitin protein ligase 2 protein
半岛bd体育手机客户端 介绍
基因名:

HECTD2


半岛bd体育手机客户端 别名:

HECTD2; HECT domain E3 ubiquitin protein ligase 2; HECT domain E3 ubiquitin protein ligase 2; probable E3 ubiquitin-protein ligase HECTD2; HECT domain containing E3 ubiquitin protein ligase 2; HECT domain-containing protein 2; HECT-type E3 ubiquitin transferase HECTD2; E3连接酶抑制素受体2;


背景信息:
HECT (Homologous to the E6-AP Carboxyl Terminus) proteins are a large group of E3 ubiquitin-ligases that play a role in the specificity and selectivity of ubiquitylation. The human genome encodes at least 20 different HECT domain proteins, which are grouped into two classes based on their E2 specificity. HECT enzymes also regulate the trafficking of many receptors, transporters, viral proteins and channels. Since HECT proteins are involved in the degradation of vital tumor suppressor molecules, it is theorized that some may contribute to tumorigenesis. HECTD2 (HECT domain-containing protein 2) is a 776 amino acid E3 ubiquitin-ligase that characteristically accepts ubiquitin from an E2 ubquitin-conjugating enzyme and directly transfers the ubiquitin to targeted substrates. Recently, HECTD2 haplotypes have been linked to the susceptibility of acquiring human prion diseases such as Creutzfeldt-Jakob Disease and kuru, which present after a long, clinically silent incubation period that seems to be determined by factors such as genetic background.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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