蛋白质/抗原/多肽 >> 重组蛋白
重组少汗型外胚层发育不良相关蛋白EDAD
半岛bd体育手机客户端 介绍
基因名:
EDARADD 半岛bd体育手机客户端 别名: ECTD11A; ECTD11B; ED3; EDA3; EDARADD; EDAR associated death domain; EDAR associated death domain; ectodysplasin-A receptor-associated adapter protein; EDAR-associated death domain protein; crinkled homolog; ectodysplasia A receptor associated death domain; 少汗型外胚层发育不良相关蛋白EDAD; 背景信息:
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
标签:His-tag |
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