蛋白质/抗原/多肽 >> 重组蛋白
重组FGD4蛋白
半岛bd体育手机客户端 介绍
基因名：
FGD4 半岛bd体育手机客户端 别名： CMT4H； FRABP； ZFYVE6； FGD4； FYVE, RhoGEF and PH domain containing 4； FYVE, RhoGEF and PH domain containing 4； FYVE, RhoGEF and PH domain-containing protein 4； FGD1 family, member 4； FGD1-related F-actin-binding protein； actin-filament binding protein frabin； zinc finger FYVE domain-containing protein 6； FGD4蛋白； 背景信息：
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq, Oct 2008]
标签：His-tag |
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