蛋白质/抗原/多肽 >> 重组蛋白
重组8号染色体开放阅读框72蛋白
半岛bd体育手机客户端 介绍
基因名:
FAM110B 半岛bd体育手机客户端 别名: C8orf72; FAM110B; family with sequence similarity 110 member B; family with sequence similarity 110 member B; protein FAM110B; 8号染色体开放阅读框72; 背景信息:
FAM110B is a 370 amino acid protein, which contains several motifs that are conserved among FAM110 family members and a proline-rich region through which it probably binds proteins. Localized to the nucleus where they associate with centrosomes, FAM110A, FAM110B and FAM110C accumulate at the spindle poles during mitosis. Expression of FAM110B and FAM110C impairs cell cycle progression through G1 phase. FAM110B is expressed in testis, thyroid and spleen and is found at lower levels in ovary, adrenal gland, stomach, trachea, intestine, lymph node, spinal cord and prostate. The gene encoding FAM110B maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
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