蛋白质/抗原/多肽 >> 重组蛋白
重组肿瘤/睾丸抗原2.4蛋白
半岛bd体育手机客户端 介绍
基因名:
BAGE4 半岛bd体育手机客户端 别名: CT2.4; MLL3P; BAGE4; BAGE family member 4; BAGE family member 4; B melanoma antigen 4; B melanoma antigen family member 4; MLL3 pseudogene; cancer/testis antigen 2.4; cancer/testis antigen family 2, member 4; 肿瘤/睾丸抗原2.4; 背景信息:
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.
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