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蛋白质/抗原/多肽 >> 重组蛋白
重组环腺苷酸应答元件结合蛋白H
重组环腺苷酸应答元件结合蛋白H图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant CREB3L3
Recombinant cAMP responsive element binding protein 3 like 3 protein
半岛bd体育手机客户端 介绍
基因名:

CREB3L3


半岛bd体育手机客户端 别名:

CREB-H; CREBH; HYST1481; HYTG2; CREB3L3; cAMP responsive element binding protein 3 like 3; cAMP responsive element binding protein 3 like 3; cyclic AMP-responsive element-binding protein 3-like protein 3; CREB/ATF family transcription factor; cAMP-responsive element-binding protein, hepatic-specific; 环腺苷酸应答元件结合蛋白H;


背景信息:
CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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