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蛋白质/抗原/多肽 >> 重组蛋白
重组PARD6G蛋白
重组PARD6G蛋白图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Recombinant PARD6G
Recombinant par-6 family cell polarity regulator gamma protein
半岛bd体育手机客户端 介绍
基因名:

PARD6G


半岛bd体育手机客户端 别名:

PAR-6G; PAR6gamma; PARD6G; par-6 family cell polarity regulator gamma; par-6 family cell polarity regulator gamma; partitioning defective 6 homolog gamma; PAR-6 gamma protein; PAR6D; par-6 partitioning defective 6 homolog gamma; PARD6G蛋白;


背景信息:
PARD6G (partitioning defective 6 homolog gamma) is a 376 amino acid adaptor protein that is involved in cell polarization and asymmetrical cell division processes. PARD6G contains one OPR domain, one PDZ (DHR) domain and one pseudo-CRIB domain. The PDZ and pseudo-CRIB domains are required for interaction with Rho small GTPases. Through its complex formation with PARD3G, PARD6G participates in the linking of GTP-bound Rho small GTPases to atypical protein kinase C (PKC) proteins. This assembly is involved in formation of normal tight junctions at epithelial cell-cell contacts. When atypical PKC and PARD6G are expressed with a constitutively active RAC, the proteins colocalize to the membrane ruffles, which are structures that occur at the leading edge of polarized cells during movement. Though widely expressed, PARD6G is found at highest levels in adult and fetal kidney.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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