蛋白质/抗原/多肽 >> 重组蛋白
重组跨膜蛋白Orai2
半岛bd体育手机客户端 介绍
基因名:
ORAI2 半岛bd体育手机客户端 别名: C7orf19; CBCIP2; MEM142B; TMEM142B; ORAI2; ORAI calcium release-activated calcium modulator 2; ORAI calcium release-activated calcium modulator 2; protein orai-2; CAP-binding protein complex interacting protein 2; H_NH0514P08.8; putative protein ORAI2-2; transmembrane protein 142B; 跨膜蛋白Orai2; 背景信息:
Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1.
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