蛋白质/抗原/多肽 >> 重组蛋白
重组染色质修饰蛋白CHMP6
半岛bd体育手机客户端 介绍
基因名：
CHMP6 半岛bd体育手机客户端 别名： VPS20； CHMP6； charged multivesicular body protein 6； charged multivesicular body protein 6； charged multivesicular body protein 6； chromatin-modifying protein 6； hVps20； vacuolar protein sorting-associated protein 20； 染色质修饰蛋白CHMP6； 背景信息：
The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. CHMP6, also known as VPS20, interacts with CHMP4 of the ESCRT-III complex. CHMP6 also interacts with SNF8, VPS25 and VPS36 of the ESCRT-II complex, where it regulates cargo sorting by acting as an acceptor for ESCRT-II on endosome membranes
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