蛋白质/抗原/多肽 >> 重组蛋白
重组19号染色体开放阅读框28蛋白
半岛bd体育手机客户端 介绍
基因名:
Mfsd12 半岛bd体育手机客户端 别名: C19orf28; F630110N24Rik; Wdt1; gr; Mfsd12; major facilitator superfamily domain containing 12; major facilitator superfamily domain containing 12; major facilitator superfamily domain-containing protein 12; protein grizzled; 19号染色体开放阅读框28; 背景信息:
C19orf28, also known as PP3501, is a multi-pass membrane protein that belongs to the major facilitator superfamily. The gene encoding C19orf28 localizes to chromosome 19 and, due to alternative splicing events, C19orf28 exists as two isoforms. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The C19orf28 gene product has been provisionally designated C19orf28 pending further characterization.
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