蛋白质/抗原/多肽 >> 重组蛋白
重组FAM123A蛋白
半岛bd体育手机客户端 介绍
基因名:
Amer2 半岛bd体育手机客户端 别名: 2600011E07Rik; Fam123a; Amer2; APC membrane recruitment 2; APC membrane recruitment 2; APC membrane recruitment protein 2; family with sequence similarity 123, member A; protein FAM123A; FAM123A蛋白; 背景信息:
The FAM123A (family with sequence similarity 123A) gene encodes for a 671 amino acid protein. There are two isoforms of FAM123A that exist as a result of alternative splicing events. The gene encoding FAM123A is located on chromosome 13, which comprises nearly 4% of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival.
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