蛋白质/抗原/多肽 >> 重组蛋白
重组DENND1C蛋白
半岛bd体育手机客户端 介绍
基因名：
Dennd1c 半岛bd体育手机客户端 别名： 4432409M07Rik； Dennd1c； DENN/MADD domain containing 1C； DENN/MADD domain containing 1C； DENN domain-containing protein 1C； connecdenn 3； DENND1C蛋白； 背景信息：
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
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