蛋白质/抗原/多肽 >> 重组蛋白
重组胆碱转运体样蛋白4
半岛bd体育手机客户端 介绍
基因名:
Slc44a4 半岛bd体育手机客户端 别名: 2210409B01Rik; NG22; mTPPT1; Slc44a4; solute carrier family 44, member 4; solute carrier family 44, member 4; choline transporter-like protein 4; thiamine pyrophosphate transporter 1; 胆碱转运体样蛋白4; 背景信息:
Choline is an essential nutrient that is required for the synthesis of both acetylcholine, a neurotransmitter found in cholinergic nerve terminals, and phosphatidylcholine, a key component of cell membranes. Choline deficiencies are associated with defects in cell growth and have been implicated in disorders such as Alzheimer’s and Parkinson’s disease. The choline transporter-like protein family (CTL) are solute carriers that transport choline, a compound which is not able to permeate cells, across the cell membrane. CTL4, also known as SLC44A4 (Solute carrier family 44 member 4), is a multi-pass membrane protein which can fuse with Neu1, generating a CTL4-Neu1 transcript. This fusion is implicated in sialidosis, a disease characterized by improper lysosomal storage.
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