鍩哄洜鍚嶏細

Mterf4

浜у搧鍒悕锛欬p style="text-indent: 2em;">1810059A23Rik锛 4933412H03Rik锛 Mterfd2锛 Mterf4锛 mitochondrial transcription termination factor 4锛 mitochondrial transcription termination factor 4锛 transcription termination factor 4, mitochondrial锛 MTERF domain containing 2锛 mTERF domain-containing protein 2锛 绾跨矑浣撹浆褰曠粓姝㈠洜瀛?锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Members of the MTERF (mitochondrial transcription termination factor) family, including MTERF, MTERFD1, MTERFD2 and MTERFD3, are mitochondrial proteins that are that thought to be transcription termination factors. MTERF (mitochondrial transcription termination factor 1) is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It is suggested that only the phosphorylated form of MTERF has transcription termination activity. MTERFD1 (MTERF domain containing 1) may play a role as a mitochondrial transcription regulator and is expressed as two isoforms produced by alternative splicing. MTERFD2 is a 381 amino acid protein that is encoded by a gene located on human chromosome 2q37.3. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription. MTERFD3 is expressed in heart, skeletal muscle, pancreas and liver.