蛋白质/抗原/多肽 >> 重组蛋白
重组BTB/POZ结构域蛋白1
半岛bd体育手机客户端 介绍
基因名:
Btbd10 半岛bd体育手机客户端 别名: 1110056N09Rik; Gmrp1; Btbd10; BTB (POZ) domain containing 10; BTB (POZ) domain containing 10; BTB/POZ domain-containing protein 10; K+ channel tetramerization protein; glucose metabolism-related protein 1; BTB/POZ结构域蛋白1; BTB/POZ结构域蛋白10; 糖代谢相关蛋白1; 背景信息:
The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD10 (BTB (POZ) domain containing 10), also known as GMRP1, is a ubiquitously expressed nuclear protein found at highest levels in adult testis, brain and small intestine and weakly expressed in colon, lung, liver, kidney, spleen,pancreas, thymus, prostate, heart and ovary. Down-regulated in glioma, BTBD10 binds PP2A (protein phosphatase 2A) to inhibit dephosphorylation of Akts and is suggested to be a suppressor of cell death as well as an enhancer of cell growth. BTBD10 contains one BTB (POZ) domain and is encoded by a gene mapping to human chromosome 11p15.2.
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