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蛋白质/抗原/多肽 >> 重组蛋白
重组肿瘤抗原CML66蛋白
重组肿瘤抗原CML66蛋白图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant Nudcd1
Recombinant NudC domain containing 1 protein
半岛bd体育手机客户端 介绍
基因名:

Nudcd1


半岛bd体育手机客户端 别名:

4921532K09Rik; AA407246; AW260430; AW556235; CML66-L; Cml66; Nudcd1; NudC domain containing 1; NudC domain containing 1; nudC domain-containing protein 1; chronic myelogenous leukemia tumor antigen 66; 肿瘤抗原CML66;


背景信息:
The NUDCD1 gene encodes the 583 amino acid CML66 protein which demonstrates expression in a variety of solid tumor cell lines and leukemias. Expression of CML66 in normal tissues is restricted to testis and heart. The CML66 antibody is found in sera of 18-38% of patients with lung cancer, melanoma or prostate cancer. These findings indicate that CML66 may be immunogenic in a wide variety of malignancies and may be a target for antigen-specific immunotherapy. A short isoform of CML66, designated CML66-S, is a product of alternative splicing. CML66-S has the same C-terminus as full-lenghth CML66 (also designated CML66-L), but has a unique N-terminus. CML66-S shows predominant expression in testis, and is also expressed in very low levels in tumor cells, while CML66 is expressed in tumor cells and testis.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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