蛋白质/抗原/多肽 >> 重组蛋白
重组DNAJC5B蛋白
半岛bd体育手机客户端 介绍
基因名:
Dnajc5b 半岛bd体育手机客户端 别名: 1700008A05Rik; Dnajc5b; DnaJ heat shock protein family (Hsp40) member C5 beta; DnaJ heat shock protein family (Hsp40) member C5 beta; dnaJ homolog subfamily C member 5B; CSP-beta; DnaJ (Hsp40) homolog, subfamily C, member 5 beta; beta cysteine string protein; beta-CSP; cysteine string protein beta; DNAJC5B蛋白; 背景信息:
The DnaJ family, one of the largest of all the chaperone families, has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat-shock induced proteins are derived from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. They are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC5B is a 199 amino acid protein that contains one J domain and plays an important role in exocytosis. DnaJC5B is expressed in testis where it is tightly bound to lipid membranes. The palmitoylation level of DnaJC5B is thought to correlate with its targeting to specific membranes.
标签:His-tag |
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