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蛋白质/抗原/多肽 >> 重组蛋白
重组纺锤体和着丝粒相关蛋白2
重组纺锤体和着丝粒相关蛋白2图片
交货期: 1周
索取资料及报价
交货期:1周
半岛bd体育手机客户端 别名:Recombinant Ska2
Recombinant spindle and kinetochore associated complex subunit 2 protein
半岛bd体育手机客户端 介绍
基因名:

Ska2


半岛bd体育手机客户端 别名:

1110001A07Rik; C78640; Fam33a; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; family with sequence similarity 33, member A; 纺锤体和着丝粒相关蛋白2;


背景信息:
Ska2 (spindle and kinetochore associated complex subunit 2), also known as FAM33A, is a 121 amino acid component of the Ska1 complex, a microtubule-binding subcomplex of the outer kinetochore that is critical for proper chromosome segregation. The Ska1 complex is a component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. Localized to the outer kinetochore and spindle microtubules during cell proliferation, Ska2 is essential for spindle checkpoint silencing and exit from mitosis. Downregulation of Ska2 leads to delayed recruitment of MAD2, a component of the mitotic spindle checkpoint, to several kinetochores resulting in occasional loss of individual chromosomes from the metaphase plate. Ska2 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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