蛋白质/抗原/多肽 >> 重组蛋白
重组胃癌多药耐药相关蛋白
半岛bd体育手机客户端 介绍
基因名：
CAPRIN2 半岛bd体育手机客户端 别名： C1QDC1； EEG-1； EEG1； RNG140； CAPRIN2； caprin family member 2； caprin family member 2； caprin-2； C1q domain-containing protein 1； RNA granule protein 140； cytoplasmic activation/proliferation-associated protein 2； gastric cancer multidrug resistance-associated protein； 胃癌多药耐药相关蛋白； 背景信息：
Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic β-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.
标签：His-tag |
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