蛋白质/抗原/多肽 >> 重组蛋白
重组DMRTA2蛋白
半岛bd体育手机客户端 介绍
基因名:
DMRTA2 半岛bd体育手机客户端 别名: DMRTA2; DMRT like family A2; DMRT like family A2; doublesex- and mab-3-related transcription factor A2; doublesex- and mab-3-related transcription factor 5; DMRTA2蛋白; 背景信息:
DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
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