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重组癌/睾丸抗原113蛋白
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介绍 基因名: TEX14 半岛bd体育手机客户端 别名: CT113; SPGF23; TEX14; testis expressed 14, intercellular bridge forming factor; testis expressed 14, intercellular bridge forming factor; inactive serine/threonine-protein kinase TEX14; cancer/testis antigen 113; protein kinase-like protein SgK307; sugen kinase 307; testis-expressed protein 14; testis-expressed sequence 14 protein; 癌/睾丸抗原113; 背景信息: TEX14 is a 1,497 amino acid protein that belongs to the protein kinase superfamily and is expressed in testis. The gene encoding TEX14 is located on chromosome 17 and is required for spermatogenesis and normal structure of the intercellular bridge that connects spermatocytes and spermatogonia. TEX14 co-localizes with the centralspindlin complex, MKLP-1 (mitotic kinesin-like protein 1) and male germ cell Rac GTPase (Rac GTPase-activating protein) and converts these midbody matrix proteins into stable intercellular bridge components. TEX14 contains 3 ANK repeats and 1 protein kinase domain. Three isoforms exist due to alternative splicing events. 标签:His-tag |
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