蛋白质/抗原/多肽 >> 重组蛋白
重组原钙粘附蛋白β6
半岛bd体育手机客户端 介绍
基因名:
PCDHB6 半岛bd体育手机客户端 别名: PCDH-BETA6; PCDHB6; protocadherin beta 6; protocadherin beta 6; protocadherin beta-6; 原钙粘附蛋白β6; 原钙黏素β6(PCDHb6); 背景信息:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
标签:His-tag |
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