蛋白质/抗原/多肽 >> 重组蛋白
重组SUPT20H蛋白
半岛bd体育手机客户端 介绍
基因名:
SUPT20H 半岛bd体育手机客户端 别名: C13; C13orf19; FAM48A; FP757; P38IP; SPT20; SUPT20H; SPT20 homolog, SAGA complex component; SPT20 homolog, SAGA complex component; transcription factor SPT20 homolog; family with sequence similarity 48, member A; protein FAM48A; suppressor of Ty 20 homolog; transcription factor (p38 interacting protein); tumor rejection antigen; 背景信息:
FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4% of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.
标签:His-tag |
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