蛋白质/抗原/多肽 >> 重组蛋白
重组NDFIP2蛋白
半岛bd体育手机客户端 介绍
基因名:
NDFIP2 半岛bd体育手机客户端 别名: N4WBP5A; NDFIP2; Nedd4 family interacting protein 2; Nedd4 family interacting protein 2; NEDD4 family-interacting protein 2; MAPK-activating protein PM04 PM05 PM06 PM07; NEDD4 WW domain-binding protein 5A; NF-kappa-B-activating protein 413; putative MAPK-activating protein PM04/PM05/PM06/PM07; putative NF-kappa-B-activating protein 413; 背景信息:
NDFIP2 is a 336 amino acid protein that localizes to the membrane of both the endosome and the golgi apparatus. Expressed in kidney, heart, brain, lung, liver, placenta and skeletal muscle, Ndfip2 interacts with NEDD4 and NEDD4-L and is thought to be involved in endocytosis and in the NFⅹB and MAPK signaling pathways. Additionally, Ndfip2 may function as an adaptor protein that may recruit NEDD4 ubiquitin-protein ligases to protein trafficking machinery in the golgi. Ndfip2 is activated by T cells and may be ubiquitinated by NEDD4 or NEDD4-L, an event that does not affect Ndfip2 function. The gene encoding Ndfip2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
标签:His-tag |
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