蛋白质/抗原/多肽 >> 重组蛋白
重组双氧化酶1/甲状腺氧化酶1蛋白
半岛bd体育手机客户端 介绍
基因名:
DUOX1 半岛bd体育手机客户端 别名: LNOX1; NOXEF1; THOX1; DUOX1; dual oxidase 1; dual oxidase 1; dual oxidase 1; NADPH thyroid oxidase 1; flavoprotein NADPH oxidase; large NOX 1; long NOX 1; nicotinamide adenine dinucleotide phosphate oxidase; thyroid oxidase 1; 双氧化酶1/甲状腺氧化酶1; 背景信息:
Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.
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