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重组剪切及多聚腺苷酸化特异因子蛋白2
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介绍 基因名: Cpsf2 半岛bd体育手机客户端 别名: 100kDa; 2610024B04Rik; AI662483; Cpsf; MCPSF; mKIAA1367; Cpsf2; cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; cleavage and polyadenylation specific factor 2, 100kD subunit; cleavage and polyadenylation specificity factor 100 kDa subunit; 剪切及多聚腺苷酸化特异因子蛋白2; 背景信息: CPSF contains four subunits and localizes to the nucleoplasm where it recognizes the AAUAAA signal in pre-mRNA and interacts with other proteins to facilitate RNA cleavage and poly(A) synthesis (1,4,5). The human CPSF2 gene maps to chromosome 14q32.12 and encodes the second largest subunit of cleavage and polyadenylation specificity factor. U1 snRNP-A protein (U1A) interacts with and affects the activity of CPSF by stabilizing the interaction of CPSF with the AAUAAA-containing RNAs to increase the efficiency of polyadenylation . 标签:His-tag |
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