蛋白质/抗原/多肽 >> 重组蛋白
重组富含脯氨酸突触相关蛋白SHANK1
半岛bd体育手机客户端 介绍
基因名:
SHANK1 半岛bd体育手机客户端 别名: SPANK-1; SSTRIP; synamon; SHANK1; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SSTR-interacting protein; somatostatin receptor-interacting protein; 富含脯氨酸突触相关蛋白SHANK1; 背景信息:
The mechanisms underlying the molecular assemblage of molecules at the synapse are not well understood. Recently, a number of novel anchoring/scaffold proteins that are associated with postsynaptic density (PSD) proteins have been isolated. SHANK1, SHANK2 and SHANK3 constitute a family of proteins that may function as molecular scaffolds in the PSD. SHANK is made of five domain/regions that are probably involved in protein-protein interactions: ankyrin repeats, an SH3 domain, a PDZ domain, a SAM domain, and a proline rich region. SHANK interacts directly with GKAP or SAPAP via its PDZ domain, thus potentially bridging the N-methyl-D-aspartate receptor (NMDA)-PSD-95-GKAP complex.
标签:His-tag |
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